Publications

2022

Prime editing efficiency and fidelity are enhanced in the absence of mismatch repair

Ferreira da Silva J, Oliveira GP, Arasa-Verge EA, Kagiou C, Moretton A, Timelthaler G, Jiricny J, Loizou JI

Nat Commun. 2022 Feb 9;13(1):760. doi: 10.1038/s41467-022-28442-1. PMID: 35140211; PMCID: PMC8828784.

2021

Double stranded DNA breaks and genome editing trigger loss of ribosomal protein

Riepe C, Zelin E, Frankino PA, Meacham ZA, Fernandez SG, Ingolia NT, Corn JE

RPS27A. FEBS J. 2021 Dec 16. doi: 10.1111/febs.16321. Epub ahead of print. PMID:34914197.


Tissue specificity of DNA repair: the CRISPR compass

Ferreira da Silva J, Meyenberg M, Loizou JI

Trends Genet. 2021 Nov;37(11):958-962. doi: 10.1016/j.tig.2021.07.010. Epub 2021 Aug 12. PMID: 34392967.


PnB Designer: a web application to design prime and base editor guide RNAs for animals and plants

Siegner SM, Karasu ME, Schröder MS, Kontarakis Z, Corn JE

BMC Bioinformatics. 2021 Mar 2;22(1):101. doi:10.1186/s12859-021-04034-6. PMID: 33653259; PMCID: PMC7923538.


2020

Targeting the DNA Repair Enzyme Polymerase θ in Cancer Therapy

Schrempf A, Slyskova J, Loizou JI

Trends Cancer. 2021 Feb;7(2):98-111. doi: 10.1016/j.trecan.2020.09.007. Epub 2020 Oct 24. PMID: 33109489.